منابع مشابه
Nonparametric Bayes Applications to Biostatistics
1. Introduction Biomedical research has clearly evolved at a dramatic rate in the past decade, with improvements in technology leading to a fundamental shift in the way in which data are collected and analyzed. Before this paradigm shift, studies were most commonly designed to be simple and to focus on relationships among a few variables of primary interest. For example, in a clinical trial, pa...
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The controversy which has surrounded the interpretation of the randomized controlled trials (RCT) of intravenous Mg 2+ in acute myocardial infarction has focused attention on the place of both meta-analysis and the mega-trial in therapeutic research. Stated simply, a fixed-effects meta-analysis of seven small controlled trials indicated a highly significant 55% reduction in odds of death among ...
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LEARNING OBJECTIVES After studying this article, the participant should be able to: 1. Recognize the various terms used in biostatistics. 2. Describe the choices that are required in designing a particular research study. 3. Understand the different types of data that may be obtained in any given study. 4. Identify which statistical tools are appropriate for evaluating the different types of da...
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In risk analysis based on Bayesian framework, premium calculation requires specification of a prior distribution for the risk parameter in the heterogeneous portfolio. When the prior knowledge is vague, the E-Bayesian and robust Bayesian analysis can be used to handle the uncertainty in specifying the prior distribution by considering a class of priors instead of a single prior. In th...
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False Discovery Rate (FDR) methodology, first put forward by Benjamini and Hochberg, and further developed by many authors including Storey, Tibshirani, and Efron is now one of the most widely used statistical methods in genomics, among other areas of application. A typical genomics workflow consists of i) estimating thousands of effects, and their associated p values; ii) feeding these p value...
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ژورنال
عنوان ژورنال: Statistical Science
سال: 1990
ISSN: 0883-4237
DOI: 10.1214/ss/1177012092